Journal of the American Academy of Child & Adolescent Psychiatry
Volume 47, Issue 10 , Pages 1166-1172 , October 2008

Neuropsychiatric Disorders Associated With Streptococcal Infection: A Case-Control Study Among Privately Insured Children

,Accepted 15 May 2008.

References 

  1. Swedo SE , Leonard HL , Garvey M , et al.   Pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections: clinical description of the first 50 cases . Am J Psychiatry . 1998;155:264–271
  2. Mercadante MT , Busatto GF , Lombroso PJ , et al.   The psychiatric symptoms of rheumatic fever . Am J Psychiatry . 2000;157:2036–2038
  3. Swedo SE , Rapoport JL , Cheslow DL , et al.   High prevalence of obsessive-compulsive symptoms in patients with Sydenham's chorea . Am J Psychiatry . 1989;146:246–249
  4. Mell LK , Davis RL , Owens D . Association between streptococcal infection and obsessive-compulsive disorder, Tourette's syndrome, and tic disorder . Pediatrics . 2005;116:56–60
  5. Leslie DL , Martin A . Health care expenditures associated with autism spectrum disorders . Arch Pediatr Adolesc Med . 2007;161:350–355
  6. Leslie DL , Rosenheck RA , Horwitz SM . Patterns of mental health utilization and costs among children in a privately insured population . Health Seerv Res . 2001;36:113–127
  7. Martin A , Leslie D . Trends in psychotropic medication costs for children and adolescents, 1997–2000 . Arch Pediatr Adolesc Med . 2003;157:997–1004
  8. Martin A , Leslie D . Psychiatric inpatient, outpatient, and medication utilization and costs among privately insured youths, 1997–2000 . Am J Psychiatry . 2003;160:757–764
  9. Martin A , Young C , Leckman JF , Mukonoweshuro C , Rosenheck R , Leslie D . Age effects on antidepressant-induced manic conversion . Arch Pediatr Adolesc Med . 2004;158:773–780
  10. Dantzer R , O'Connor JC , Freund GG , Johnson RW , Kelley KW . From inflammation to sickness and depression: when the immune system subjugates the brain . Nat Rev Neurosci . 2008;9:46–56
  11. Peterson BS , Leckman JF , Tucker D , et al.   Preliminary findings of antistreptococcal antibody titers and basal ganglia volumes in tic, obsessive-compulsive, and attention deficit/hyperactivity disorders . Arch Gen Psychiatry . 2000;57:364–372
  12. Cohen P , Pine DS , Must A , Kasen S , Brook J . Prospective associations between somatic illness and mental illness from childhood to adulthood . Am J Epidemiol . 1998;147:232–239
  13. Fernandez-Rivas A , Terreros MT , Ibarmia J , Lantaron G , Gonzalez-Torres MA . Recurrent depression: infectious-autoimmune etiology? . Am Acaad Child Adolesc Psychiatry . 2000;39:810–812
  14. Luo F , Leckman JF , Katsovich L , et al.   Prospective longitudinal study of children with tic disorders and/or obsessive-compulsive disorder: relationship of symptom exacerbations to newly acquired streptococcal infections . Pediatrics . 2004;113:e578–e585
  15. Kurlan R , Johnson D , Kaplan EL , the Tourette Syndrome Study Group  . Streptococcal infection and exacerbations of childhood tics and obsessive-compulsive symptoms: a prospective blinded cohort study . Pediatrics . 2008;121:1188–1197
  16. Allen AJ , Leonard HL , Swedo SE . Case study: a new infection-triggered, autoimmune subtype of pediatric OCD and Tourette's syndrome . J Am Acad Child Adolesc Psychiatry . 1995;34:307–311
  17. Hoekstra PJ , Manson WL , Steenhuis MP , Kallenberg CG , Minderaa RB . Association of common cold with exacerbations in pediatric but not adult patients with tic disorder: a prospective longitudinal study . J Child Adolesc Psychopharmacol . 2005;15:285–292
  18. Cherry JD , Shapiro NL , Deville JG . Sinusitis . In:  Feigin RD ,  Cherry JD ,  Demmler GJ ,  Kaplan SL editor. Textbook of Pediatric Infectious Diseases . 5th ed.. Philadelphia: Saunders; 2004;p. 201
  19. Khalifa N , von Knorring AL . Psychopathology in a Swedish population of school children with tic disorders . J Am Acad Child Adolesc Psychiatry . 2006;45:1346–1353
  20. Biederman J . Attention-deficit/hyperactivity disorder: a selective overview . Biol Psychiatry . 2005;57:1215–1220
  21. Charmandari E , Kino T , Souvatzoglou E , Chrousos GP . Pediatric stress: hormonal mediators and human development . Horm Res . 2003;59:161–179
  22. Jaffee SR , Moffitt TE , Caspi A , Fombonne E , Poulton R , Martin J . Differences in early childhood risk factors for juvenile-onset and adultonset depression . Arch Gen Psychiatry . 2002;59:215–222
  23. Lin H , Katsovich L , Ghebremichael M , et al.   Psychosocial stress predicts future symptom severities in children and adolescents with Tourette syndrome and/or obsessive-compulsive disorder . J Child Psychol Psychiatry . 2007;48:157–166
  24. MacMaster FP , Russell A , Mirza Y , et al.   Pituitary volume in treatmentnaïve pediatric major depressive disorder . Biol Psychiatry . 2006;60:862–866
  25. Lougee L , Perlmutter SJ , Nicolson R , Garvey MA , Swedo SE . Psychiatric disorders in first-degree relatives of children with pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections (PANDAS) . J Am Acad Child Adolesc Psychiatry . 2000;39:1120–1126
  26. Bolton D , Rijsdijk F , O'Connor TG , Perrin S , Eley TC . Obsessive-compulsive disorder, tics and anxiety in 6-year-old twins . Psychol Med . 2007;37:39–48
  27. Khan SA , Faraone SV . The genetics of ADHD: a literature review of 2005 . Curr Psychiatry Rep . 2006;8:393–397
  28. Rice F , Harold G , Thapar A . The genetic aetiology of childhood depression: a review . J Child Psychol Psychiatry . 2002;43:65–79

 This article was reviewed under and accepted by Ad Hoc Editor Daniel S. Pine, M.D.This research was supported in part by NIH grants MH049351, MH061940, and MH076273. Additional support was provided by the Richmand and Kaiser Families.

PII: S0890-8567(08)60102-1

doi: 10.1097/CHI.0b013e3181825a3d

Journal of the American Academy of Child & Adolescent Psychiatry
Volume 47, Issue 10 , Pages 1166-1172 , October 2008