Journal of the American Academy of Child & Adolescent Psychiatry
Volume 47, Issue 1 , Pages 2-3 , January 2008

Defining the Contribution of Genetic Risk to Structural and Functional Anomalies in ADHD

  • JUDITH L. RAPOPORT, M.D.

      Affiliations

    • Corresponding Author InformationCorrespondence to Dr. Judith Rapoport, National Institute of Mental Health, 9000 Rockville Pike, Bethesda, MD 20892
    • ,
  • PHILIP SHAW, M.D., Ph.D.

,Accepted 4 September 2007.

REFERENCES 

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  2. Mulder MJ , Baeyens D , Davidson MC , et al.   Familial vulnerability for ADHD affects activity in cerebellum in addition to prefrontal systems . J Am Acad Child Adolesc Psychiatry . 2008;69–76
  3. Zametkin AJ , Nordahl TE , Gross M , et al.   Cerebral glucose metabolism in adults with hyperactivity of childhood onset . N Engl J Med . 1990;323:1361–1366
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  6. Durston S . A review of the biological bases of ADHD: what have we learned from imaging studies? . Ment Retard Dev Disabil Res Rev . 2003;9:184–195
  7. Durston S , Hulshoff Pol HE , Schnack HG , et al.   Magnetic resonance imaging of boys with attention-deficit/hyperactivity disorder and their unaffected siblings . J Am Acad Child Adolesc Psychiatry . 2004;43:332–340
  8. Mill J , Caspi A , Williams BS , et al.   Prediction of heterogeneity in intelligence and adult prognosis by genetic polymorphisms in the dopamine system among children with attention-deficit/hyperactivity disorder: evidence from 2 birth cohorts . Arch Gen Psychiatry . 2006;63:462–469
  9. Bellgrove MA , Hawi Z , Kirley A , et al.   Association between dopamine transporter (DAT1) genotype, left-sided inattention, and an enhanced response to methylphenidate in attention-deficit hyperactivity disorder . Neuropsychopharmacology . 2005;30:2290–2297
  10. Vaidya CJ , Austin G , Kirkorian G , et al.   Selective effects of methylphenidate in attention deficit hyperactivity disorder: a functional magnetic resonance study . Proc Natl Acad Sci U S A . 1998;95:14494–14499
  11. Desmond JE . Neuroimaging studies of the cerebellum: language, learning, and memory . Trends Cogn Sci . 1998;2:355–362
  12. Mackie S , Shaw P , Lenroot R , et al.   Cerebellar development and clinical outcome in attention deficit hyperactivity disorder . Am J Psychiatry . 2007;164:647–655

PII: S0890-8567(09)62078-5

doi: 10.1097/chi.0b013e31815aac83

Journal of the American Academy of Child & Adolescent Psychiatry
Volume 47, Issue 1 , Pages 2-3 , January 2008

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