Journal of the American Academy of Child & Adolescent Psychiatry
Volume 47, Issue 4 , Pages 390-398, April 2008

Depression in Men in the Postnatal Period and Later Child Psychopathology: A Population Cohort Study

Drs. Ramchandani and Stein are with the Section of Child and Adolescent Psychiatry, University of Oxford; Dr. O'Connor is with the Department of Psychiatry, University of Rochester; Dr. Heron is with the Department of Social Medicine and Dr. Evans is with the Academic Unit of Psychiatry, University of Bristol; and Dr. Murray is with the Winnicott Research Unit, University of Reading.

Accepted 10 October 2007.

ABSTRACT 

Objective

Postnatal depression in women is associated with adverse effects on both maternal health and children's development. It is unclear whether depression in men at this time poses comparable risks. The present study set out to assess the association between depression in men in the postnatal period and later psychiatric disorders in their children and to investigate predisposing factors for depression in men following childbirth.

Method

A population-based cohort of 10,975 fathers and their children from the Avon Longitudinal Study of Parents and Children (ALSPAC) was recruited in the prenatal period and followed for 7 years. Paternal depressive symptoms were assessed with the Edinburgh Postnatal Depression Scale and later child psychiatric disorder (DSM-IV) with the Development and Well-Being Assessment.

Results

Depression in fathers in the postnatal period was significantly associated with psychiatric disorder in their children 7 years later (adjusted OR 1.72, 95% CI 1.07-2.77), most notably oppositional defiant/conduct disorders (adjusted OR 1.94, 95% CI 1.04-3.61), after adjusting for maternal depression and paternal educational level. A history of severe depression and high prenatal symptom scores for depression and anxiety were the strongest predictors of paternal depression in the postnatal period.

Conclusions

Depression in fathers in the postnatal period is associated with later psychiatric disorders in their children, independently of maternal postnatal depression. Further research into the risks associated with paternal psychopathology is required because this could represent an important opportunity for public health intervention.

Key Words:  depression , fathers , psychiatric disorder

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 This research was specifically funded by the Wellcome Trust through an Intermediate Clinical Fellowship held by Dr. Ramchandani (grant number 078434). Dr. Stein is also supported by the Wellcome Trust (066008) and Dr. Murray is supported by the MRC (UK). We are extremely grateful to all of the families who took part in this study, the midwives for their help in recruiting them, and the whole ALSPAC team, which includes interviewers, computer and laboratory technicians, clerical workers, research scientists, volunteers, managers, nurses, and receptionists. The UK Medical Research Council, the Wellcome Trust, and the University of Bristol provide core support for ALSPAC.Article Plus (online only) materials for this article appear on the Journal's Web site: www.jaacap.com.Disclosure: Drs. Ramchandani, Stein, O'Connor, Heron, and Murray report no conflicts of interest. Dr. Evans has been a paid speaker for Lilly Pharmaceuticals.

PII: S0890-8567(09)62394-7

doi:10.1097/CHI.0b013e31816429c2

Journal of the American Academy of Child & Adolescent Psychiatry
Volume 47, Issue 4 , Pages 390-398, April 2008