Cognitive Inflexibility and Frontal-Cortical Activation in Pediatric Obsessive-Compulsive Disorder

 This article was reviewed under and accepted by Ad Hoc Editor David R. Rosenberg, M.D.

 This research was supported by the David Judah Fund (J.C.B., S.E.S.) and in part by the Intramural Research Program of the National Institutes of Health and the National Institute of Mental Health (J.C.B., D.S.P., E.L.).

 Disclosure: Dr. Rauch has received funds for research through Massachusetts General Hospital (MGH) from Medtronics, Cyberonics, and Cephalon. He has received honoraria from Novartis, Neurogen, Sepracor, Primedia, and Medtronics, Inc. Dr. Rauch is a trustee at McLean Hospital and serves on the Board at the Massachusetts Society for Medical Research (MSMR) as well as on the National Foundation of Mental Health (NFMH) Board. Dr. Killgore works as a part-time contract researcher at the Department of Defense Contractor, GovSource, Inc., and does contract work for the Brain Institute, University of Utah. He has a U.S. Army Medical Research and Material Command grant and a patent pending: The Sleep History and Readiness Predictor (SHARP), a computer program developed for predicting cognitive performance from sleep and circadian rhythms. Dr. Killgore is affiliated with the U.S. Army Reserve. Dr. Pauls has obtained funds from the following sources: National Institutes of Health (National Institute of Neurological Disorders and Stroke, and National Institute of Mental Health), Autism Consortium, Ellison Foundation, Anonymous Donor, and has received an honorarium from the Mayo Clinic for giving course lectures. Drs. Britton, Rosso, Ragan, Chosak, Pine, Leibenluft, Jenike, and Stewart, and Ms. Price, and Ms. Hezel report no biomedical financial interests or potential conflicts of interest.

PII: S0890-8567(10)00416-8

doi:10.1016/j.jaac.2010.05.006

© 2010 American Academy of Child and Adolescent Psychiatry. Published by Elsevier Inc. All rights reserved.